This panel contains the following tests:
- Atypical perinuclear antineutrophil cytoplasmic antibodies (pANCA)
- Saccharomyces cerevisiae, IgA
- Saccharomyces cerevisiae, IgG
Inflammatory bowel disease (IBD) is a chronic disorder of the lower gastrointestinal tract that may occur in three forms: Crohn's disease, ulcerative colitis, and indeterminate colitis. This panel can be useful in differentiating between which form of IBD.
Nearly 80% of people who have Crohn's disease are positive for either IgA or IgG antibodies to S. cerevisiae (a type of yeast). In ulcerative colitis, <15% are positive for IgG, and <2% are positive for IgA. The atypical ANCA pattern has been observed in a significant percentage of patients with ulcerative colitis.
Fasting is not required for this test. Take all medications as prescribed.
This panel is for screening purposes only and results should be used in conjunction with other clinical and laboratory testing for a definitive diagnosis.